Stress Testing in Asymptomatic Aortic Stenosis.

Stress Testing in Patients with Asymptomatic Severe Aortic Stenosis

Meta-analysis of prognostic value of stress testing in patients with asymptomatic severe aortic stenosis.

The management strategy in asymptomatic patients with severe aortic stenosis (AS) is controversial. Aortic valve replacement has significant morbidity and mortality, while there is a risk for sudden cardiac death with conservative management. There is no consensus on the prognostic value of stress testing to stratify management. A pooled analysis of studies in patients with severe AS was perfor...

Management of Asymptomatic Severe Aortic Stenosis

Patients with symptomatic severe aortic stenosis (AS) benefit from aortic valve replacement surgery, but the management of patients with asymptomatic severe AS is more controversial. While cholesterol and angiotensin have been linked to AS progression, we should await the results of ongoing randomized trials before medical therapy to lower cholesterol or inhibit angiotensin can be recommended t...

Exercise testing in asymptomatic severe aortic stenosis.

The management and the clinical decision making in asymptomatic patients with aortic stenosis are challenging. An "aggressive" management, including early aortic valve replacement, is debated in these patients. However, the optimal timing for surgery remains controversial due to the lack of prospective data on the determinants of aortic stenosis progression, multicenter studies on risk stratifi...

Treatment decision in asymptomatic aortic valve stenosis: role of exercise testing.

OBJECTIVE To determine the prognostic value of exercise testing, valve area, and maximum transaortic pressure gradient in asymptomatic patients with aortic valve stenosis. SETTING The outpatient service of a tertiary referral centre for cardiology. DESIGN Prospective clinical study. PATIENTS 66 consecutive patients with isolated severe aortic stenosis (aortic valve area </= 1.0 cm(2)) wer...